MOTS-c
Mitochondrial peptide activating the AMPK pathway — insulin sensitivity and metabolic research
Coenzyme in 500+ enzymatic reactions — longevity research published in Cell and Nature
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NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells and participates in over 500 distinct enzymatic reactions. It serves as the primary electron carrier in cellular respiration and is an essential cofactor for sirtuins (longevity-associated deacetylases) and PARP enzymes (DNA repair). Research published in Cell, Nature, and Science has established that NAD+ levels decline significantly with age in both rodents and humans, and that restoration of NAD+ has systemic effects on metabolic health, DNA repair, and mitochondrial function. Supplied as high-purity lyophilised powder.
Key publications include Imai S. & Guarente L., "NAD+ and sirtuins in aging and disease", Trends in Cell Biology (2014); Mills K.F. et al., "Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline", Cell Metabolism (2016); Verdin E., "NAD+ in Aging, Metabolism, and Neurodegeneration", Science (2015).
Mitochondrial peptide activating the AMPK pathway — insulin sensitivity and metabolic research
Nootropic peptide with GABAergic modulation — developed by the Russian Academy of Sciences