For Research Use Only — Not for Human Consumption
Semax research peptide vial UK
>99% Purity EU Warehouse

Semax

ACTH(4-10) analogue with BDNF/NGF modulation — 20+ years of published research

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Temperature: -20°C (lyophilised) / 2–8°C (solution)
Conditions: Protect from light
Shelf Life: 24 months (lyophilised)

Research Profile

Semax is a synthetic heptapeptide analogue of ACTH(4-10) (sequence Met-Glu-His-Phe-Pro-Gly-Pro) developed at the Institute of Molecular Genetics, Russian Academy of Sciences. Unlike ACTH, Semax lacks adrenocorticotropic activity. Research focus centres on its neurotropic properties: it upregulates BDNF (brain-derived neurotrophic factor) and NGF (nerve growth factor), promotes hippocampal neuroplasticity, and has demonstrated neuroprotective effects in ischaemia models. The peptide is registered as a pharmaceutical in Russia for neurological applications. Outside Russia, it is a research compound with a substantial body of published literature.

Key Research Findings

  • ACTH(4-10) analogue without adrenocorticotropic activity
  • Upregulates BDNF and NGF expression in hippocampal tissue
  • Neuroprotective effects documented in cerebral ischaemia rodent models
  • Modulates dopamine and serotonin receptor sensitivity
  • Registered pharmaceutical in Russia — 20+ years published research

Miasoedov N.F. et al., Institute of Molecular Genetics, Russian Academy of Sciences. 20+ years of published research including ischaemia models, BDNF upregulation studies, and cognitive performance assays in rodents.

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